Vaccines Information

The following information is for those seeking vaccinations in the City of St. Louis. If you are seeking vaccination records, please call (314) 657-1548.


The City of St. Louis Department of Health recommends that all residents keep up with their vaccines, especially COVID-19, influenza, and the vaccines that are required for children to attend school.

Prior to vaccines, it was common for people to die from diseases that are now preventable by vaccines, including measles, polio and whooping cough. Immunizations not only protect individual people, but aid in protecting the health of our community, especially those individuals who cannot be immunized.

See below for information on vaccines, school immunizations and more.

COVID-19 Vaccinations

Vaccines are now available to everyone ages 6 months and over. FEMA and the City of St. Louis recommend going to and entering your ZIP code for the nearest convenient location to receive a vaccine.

You can use the Missouri COVID-19 Vaccine Navigator to register and schedule appointments for vaccinations. Use the website to register, or call the state’s COVID-19 hotline at (877) 435-8411 for assistance.

Visit the COVID-19 Vaccine Information website

Influenza Vaccinations

The City of St. Louis Department of Health and the Centers for Disease Control and Prevention recommend a yearly flu vaccine for everyone 6 months of age and older as the first and most important step in protecting against this serious disease.

Please visit our free Flu Shot Clinic locator for dates, times, and registration links (if applicable). 

Visit the Influenza (flu) Vaccine Information website


Mpox Vaccine

The MPOX virus continues to spread in the St. Louis region and the regional local public health departments are working diligently with local clinic partners to provide MPOX vaccinations.

The Missouri Department of Health and Senior Services (DHSS) has recently expanded eligibility for MPOX vaccination to include anyone who is likely to be exposed to MPOX (sometimes referred to as pre-exposure prophylaxis or PrEP). The vaccination is a two-dose series, 28 days apart, and helps prevent the spread of MPOX. 

Anybody who meets any of the criteria below are now eligible for MPOX vaccine: 

  • Gay, bisexual, and other men who have sex with men and transgender or nonbinary people who in the past 6 months have had
    • A new diagnosis of one or more nationally reportable sexually transmitted diseases (i.e., acute HIV, chancroid, chlamydia, gonorrhea, or syphilis) and/or
    • More than one sex partner
  • People who have had any of the following in the past 6 months:
    • Sex at a commercial sex venue
    • Sex in association with a large public event in a geographic area where MPOX transmission is occurring (this currently includes the St. Louis metro region)
  • Sexual partners of people with the above risks
  • People who anticipate experiencing the above risks
  • People who know one of their sexual partners in the past 2 weeks has been diagnosed with MPOX


Vaccines are available at the following locations for those who meet the above criteria. Please bring your insurance card (if you have insurance) and a photo ID to your vaccine appointment. All the locations below will provide vaccination if you do not have insurance.

  • Affinia Healthcare
    • Call 314-814-8700 to inquire
    • Affinia will offer the Mpox vaccine on Thursdays 9-11:45 a.m., and Fridays from 9 a.m.-2 p.m., at its midtown location, 2900 Washington Ave.
  • SSM Health
    • Call 314-955-9600 to schedule vaccination
    • Vaccines are available at SSM Health locations in Rock Hill, Florissant, Arnold, and O’Fallon
  • Southampton Healthcare

Respiratory Syncytial Virus (RSV) Immunizations

Respiratory syncytial (sin-SISH-uhl) virus, or RSV, is a common respiratory virus that usually causes mild, cold-like symptoms. Most people recover in a week or two, but RSV can be serious. Infants and older adults are more likely to develop severe RSV and need hospitalization. Vaccines are available to protect older adults from severe RSV. Monoclonal antibody products are available to protect infants and young children from severe RSV. CDC Recommends:

Adults 60 years old and over:

  • Adults 60 years of age and older may receive a single dose of RSV vaccine using shared clinical decision-making.

Infants and young children:

  • 1 dose of nirsevimab for all infants younger than 8 months born during or entering their first RSV season.
  • 1 dose of nirsevimab for infants and children 8–19 months old who are at increased risk for severe RSV disease and entering their second RSV season.

RSV vaccines are available for those 60 and over at Walgreens, Wal-Mart, or by contacting your healthcare provider.

If you have any questions about RSV or the products above, talk to your healthcare provider.



CDC recommends that adults 50 years and older get two doses of the shingles vaccine called Shingrix (recombinant zoster vaccine) to prevent shingles and the complications from the disease. Adults 19 years and older who have weakened immune systems because of disease or therapy should also get two doses of Shingrix, as they have a higher risk of getting shingles and related complications.

Shingles vaccines are available for those 50 and over at Walgreens, Wal-Mart, CVS, or by contacting your healthcare provider.


School Immunizations

Missouri State law and health regulations require students to be properly immunized and provide verification to attend school, unless they have an appropriate exemption card on file. Children attending school must be immunized against diphtheria, tetanus, pertussis, meningococcal, polio, measles, mumps, rubella, hepatitis B and varicella. All students are required to provide documentation that includes the month, day and year the vaccine was administered.

2023 - 2024 School Requirements | En Español | На русском

School Immunization Schedules

Vaccine Education

SARS-CoV-2 is the name of the coronavirus strain that causes the respiratory disease known as COVID-19.The vaccine toolkit was created in collaboration with the Saint Louis Science Center to help increase awareness and understanding about vaccines in disease prevention. 

Use the vaccination education toolkit by downloading and printing the information needed for your vaccines education campaign.

Immunization Exemptions for Minors

The Department of Health offers immunization exemptions for minor children. Parent/Guardian Immunization Exemption documents and Immunization Exemption requests for religious reasons are available on a walk-in basis from 9:00 a.m.-12:00 p.m. Monday-Friday (except city holidays). All other encounters will be by appointment only. City residents may call 314-657-1475 to make an appointment.

Anyone seeking exemptions due to medical reasons or related to COVID-19 must contact their health care provider.

Note: A parent/guardian immunization exemption is usually secured for daycare aged children and must be renewed annually.

Obtain Your Personal Vaccine Information from Medical Records

By calling (314) 657-1548

  • Services available from 8:30 a.m.-5:00 p.m. Monday-Friday. Closed on City Holidays.
  • Provides records for Hepatitis, immunizations, lead, and closed City hospitals
  • $10 Fee per Record (cash only, please have exact change)


Hepatitis A Vaccinations

City of St. Louis ordinance #68597 states every holder of a PERMIT for a FOOD ESTABLISHMENT, operating for more than ten days, shall verify a certificate of immunization from a health care provider for the Hepatitis A virus from every EMPLOYEE assigned to the preparation, display or service of FOOD for such FOOD ESTABLISHMENT within thirty (30) days after the commencement of such EMPLOYEE'S employment. Additional information on this ordinance is available online.

The following clinics offer Hepatitis A vaccinations.

  • Betty Jean Kerr People's Health Center
    5701 Delmar - 314-367-7848
    Payment for the vaccination is based on a sliding scale.
  • Walgreens Take Care Clinic
    Hepatitis A series (adult) ages 19+
    $113.99 per dose, 2 dose series

Additional resources are listed on the Mercy Neighborhood Ministry website.


Travel Vaccinations

The Centers for Disease Control and Prevention's Travelers' Health website offers information on recommended vaccinations and health notices. 

Travelling for Work? 

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