COVID-19 Vaccine Third Dose or Booster Guide

Eligibility information about third dose or booster shots of the COVID-19 vaccine

Overview

Update (4/1/2022): The U.S. Food and Drug Administration and the Missouri Department of Health and Senior Services have released guidance authorizing second boosters for certain populations. 

Those who are 12 or older and fully vaccinated against COVID-19 are eligible for a booster shot:

  • At least 5 months after a 2-dose primary series of Pfizer BioNTech

Those who are 18 or older and fully vaccinated against COVID-19 are eligible for a booster shot:

  • At least 2 months after a 1-dose vaccine of Janssen/Johnson & Johnson, or
  • At least 5 months after a 2-dose primary series of Pfizer BioNTech, or Moderna COVID-19 vaccines

hose who are 50 or older and fully vaccinated and boosted against COVID-19 are eligible for a second booster shot:

  • At least 4 months after the first booster dose of Pfizer BioNTech, or Moderna COVID-19 vaccines

You may choose which COVID-19 vaccine you receive as a booster shot. Some people may have a preference for the vaccine type that they originally received, and others may prefer to get a different booster. Children between the ages of 12-17 may only receive the Pfizer BioNTech vaccine.

Remember to bring your CDC Vaccination Record Card!

If you have lost your vaccination card, you will need to contact our Medical Records office to request a vaccination record. Cost: $10, cash only.

Vaccine Clinics

*Type of vaccine(s) are listed in each event
(when information is provided to DOH)

View more COVID-19 Vaccine Clinics

Learn more on the State of Missouri Vaccine Navigator website or
call (877) 435-8411

For COVID-19 related questions, call (314) 657-1499 or email health@stlouis-mo.gov.

Eligibility

If you have received two doses of the Pfizer or Moderna COVID-19 vaccine:

You are eligible to receive a Pfizer or Moderna COVID-19 booster vaccination if you are:

  • 16-17 years old (Pfizer only)
  • 18+ years old (Pfizer or Modera)
  • 12+ years old and moderately to severely immunocompromised (Pfizer only)
  • Vaccinated six or more months ago

If you have received one dose of the Johnson & Johnson COVID-19 vaccine:

You are eligible to receive a Johnson & Johnson COVID-19 booster vaccination if you are:

  • 18+ years old and who were vaccinated two or more months ago

Can you receive a different vaccine from your initial series?

If the same vaccine is not available, a mixed series of mRNA COVID-19 or a dose of Janssen COVID-19 vaccine may be administered spaced appropriately for boosters. (Individuals under 18 years old may ONLY receive the Pfizer vaccine at this time.)

Third Dose:

A third dose of the Pfizer (12 and up) or Moderna (18 and up) vaccines may be administered 28 days after a second dose to moderately to severely immunocompromised people due to a medical condition or combination of immunosuppressive medication or treatments. Read more about qualifying conditions.

If you DO NOT meet the guidelines above:

At this time, there is not enough data to prove an additional dose will benefit you.

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