COVID-19 Vaccine Third Dose or Booster Guide

Eligibility information about third dose or booster shots of the COVID-19 vaccine


  • People 65 years and older, 50–64 years with underlying medical conditions, or 18 years and older who live in long-term care settings should receive a booster shot.
  • People 18 years and older should receive a booster shot at least 2 months after receiving their Johnson & Johnson/Janssen COVID-19 vaccine.

You may choose which COVID-19 vaccine you receive as a booster shot. Some people may have a preference for the vaccine type that they originally received, and others may prefer to get a different booster. CDC’s recommendations now allow for this type of mix and match dosing for booster shots.

For COVID-19 related questions, call (314) 657-1499 or email

Be sure to bring your CDC Vaccination Record Card!


If you have received two doses of the Pfizer or Moderna COVID-19 vaccine:

You are eligible to receive a Pfizer or Moderna COVID-19 booster vaccination if you are:

  • 65+ years old
  • 18+ years old and:
    • Reside in a long-term care facility, or
    • Have underlying medical conditions, or
    • Are at increased risk at your work or living space
  • 12+ years old and moderately to severely immunocompromised (Pfizer only)
  • Vaccinated six or more months ago

If you have received one dose of the Johnson & Johnson COVID-19 vaccine:

You are eligible to receive a Johnson & Johnson COVID-19 booster vaccination if you are:

  • 18+ years old and who were vaccinated two or more months ago

Can you receive a different vaccine from your initial series?

If the same vaccine is not available, a mixed series of mRNA COVID-19 or a dose of Janssen COVID-19 vaccine may be administered spaced appropriately for boosters.

If you DO NOT meet the guidelines above:

At this time, there is not enough data to prove an additional dose will benefit you.

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